Effects of Polyvinylpyrrolidone on In Vitro Melamine-Cyanurate Crystal Formation : An Electron Microscopy Study
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- TAKSINOROS Sarawut
- Division of Engineering (Biotechnology), Graduate School of Engineering, Kyoto Sangyo University, Kamigamo, Kita-ku, Kyoto, Kyoto 603–8555, Japan
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- MURATA Hideo
- Faculty of Life Sciences, Kyoto Sangyo University, Kamigamo, Kita-ku, Kyoto, Kyoto 603–8555, Japan
書誌事項
- タイトル別名
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- Effects of Polyvinylpyrrolidone on <i>In Vitro</i> Melamine-Cyanurate Crystal Formation: An Electron Microscopy Study
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抄録
Melamine-cyanurate (M-C) crystals, formed by melamine and cyanuric acid, are water-insoluble urolites that can cause renal tubule occlusion, leading to kidney failure. The morphology of the crystals in vivo differs from that in vitro, being rounded in the former case but needle-like in the latter. The reason for this difference remains unknown, but we have previously found that serum proteins, such as bovine serum albumin (BSA), can contribute to in vitro formation of rounded M-C crystals. In the present study, using scanning electron microscopy, we confirmed that, like BSA, polyvinylpyrrolidone (PVP), a synthetic macromolecule, can alter the crystal morphology to a spherical form. The size and surface structure differed between BSA- and PVP-induced M-C crystals.
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 75 (5), 653-655, 2013
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681404544896
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- NII論文ID
- 130002502174
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- NII書誌ID
- AA10796138
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- COI
- 1:STN:280:DC%2BC3s3hvVaksg%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 024676552
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- PubMed
- 23238455
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可