Infectivity of Cryptosporidium andersoni and Cryptosporidium muris to Normal and Immunosuppressive Cynomolgus Monkeys
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- MASUNO Koichi
- Drug Developmental Research Laboratories, Shionogi & Co., Ltd., 3–1–1, Futaba-Cho, Toyonaka, Osaka 561–0825, Japan Veterinary Medicine, Gifu University, 1–1 Yanagido, Gifu, Gifu 501–1194, Japan
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- FUKUDA Yasuhiro
- Laboratory of Sustainable Environmental Biology, Graduate School of Agricultural Science, Tohoku University, Naruko-Onsen, Osaki, Miyagi 989–6711, Japan
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- KUBO Masahito
- Veterinary Medicine, Gifu University, 1–1 Yanagido, Gifu, Gifu 501–1194, Japan Laboratory of Veterinary Pathology, Yamaguchi University, 1677–1 Yoshida, Yamaguchi-City, Yamaguchi 753–8511, Japan
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- IKARASHI Ryo
- Laboratory of Sustainable Environmental Biology, Graduate School of Agricultural Science, Tohoku University, Naruko-Onsen, Osaki, Miyagi 989–6711, Japan
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- KURAISHI Takeshi
- The Institute of Medical Science, The University of Tokyo, 4–6–1 Shirogane-dai, Minato-ku, Tokyo 108–8639, Japan
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- HATTORI Shosaku
- The Institute of Medical Science, The University of Tokyo, 4–6–1 Shirogane-dai, Minato-ku, Tokyo 108–8639, Japan
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- KIMURA Junpei
- Korea Secretary General of Asian Society of Zoo and Wildlife Medicine, College of Veterinary Medicine, Seoul National University, Seoul 151–742, Korea
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- KAI Chieko
- The Institute of Medical Science, The University of Tokyo, 4–6–1 Shirogane-dai, Minato-ku, Tokyo 108–8639, Japan
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- YANAI Tokuma
- Veterinary Medicine, Gifu University, 1–1 Yanagido, Gifu, Gifu 501–1194, Japan
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- NAKAI Yutaka
- Laboratory of Sustainable Environmental Biology, Graduate School of Agricultural Science, Tohoku University, Naruko-Onsen, Osaki, Miyagi 989–6711, Japan
書誌事項
- タイトル別名
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- Infectivity of <i>Cryptosporidium andersoni</i> and <i>Cryptosporidium muris</i> to Normal and Immunosuppressive Cynomolgus Monkeys
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Cryptosporidium andersoni and Cryptosporidium muris infections have been found in the mice and/or cattle. The oocysts of C. andersoni and C. muris have been sporadically detected in human feces, but the infectious capacity and features have been unknown, because of the scarcity of reports involving human infections. To assess the infectivity and the clinical and pathological features of C. andersoni and C. muris in primates, an experimental infectious study was conducted using cynomolgus monkeys. The monkeys were orally inoculated with oocysts of two different C. andersoni Kawatabi types and C. muris RN-66 under normal and immunosuppressive conditions. The feces of the monkeys were monitored for about 40 days after the administration of oocysts using the flotation method, but no shedding oocysts were observed under either both normal or immunosuppressive conditions. Gross and histopathological examinations were performed on the immunosuppressive monkeys, but these revealed no evidence of Cryptosporidium infections, even though the monkeys were subjected to immunosuppressive conditions. It is hypothesized that C. andersoni and C. muris pose little danger of infection in primates even under immunosuppressive conditions.
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 76 (2), 169-172, 2014
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681405230336
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- NII論文ID
- 130003382357
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- NII書誌ID
- AA10796138
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- COI
- 1:STN:280:DC%2BC2c%2Flt1ajtg%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 025296836
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- PubMed
- 24132296
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可