Determination of Optimal Dose of Arginine Vasopressin in Hemorrhagic Shock in Dogs
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- YOO Jong-Hyun
- BK21 Program of Integrative Network Systems for Veterinarians in Basic Science, Industrial Animals and Preventive Medicines, Konkuk University
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- PARK Chul
- Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University
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- HAHM Dae-Hyun
- Acupuncture & Meridian Science Research Center, Kyung-Hee University Institute of Oriental Medicine, College of Korean Medicine, Kyung-Hee University
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- LEE Hye-Jung
- Acupuncture & Meridian Science Research Center, Kyung-Hee University Institute of Oriental Medicine, College of Korean Medicine, Kyung-Hee University
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- PARK Hee-Myung
- Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University
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抄録
The hemodynamic effects of vasopressin of high/low doses on dogs were investigated using experimentally induced hemorrhagic shock model. Experimental groups were categorized according to administered doses of vasopressin (0.1, 0.4 and 1.6 IU/kg) and hemodynamic parameters were measured before and after the graded-dose administration of vasopressin. Administration of high- and middle-dose vasopressin (0.4 and 1.6 IU/kg) showed superior increase in blood pressure and systemic vascular resistance, compared with those of low-dose one (0.1 IU/kg). Results of systolic arterial pressure and mean arterial pressure in 1.6 IU/kg-administered group revealed lower efficacy than that in 0.4 IU/kg group in spite of administration of higher dose. This study demonstrates that 0.4 IU/kg of vasopressin can be used as the most effective dose for improving hemodynamic condition in the decompensatory phase of hemorrhagic shock in dogs.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 69 (7), 755-758, 2007
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681406325120
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- NII論文ID
- 110006366687
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 8896319
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- 抄録ライセンスフラグ
- 使用不可