Avian Pathology : The Efficacy of Artesunate, Chloroquine, Doxycycline, Primaquine and a Combination of Artesunate and Primaquine against Avian Malaria in Broilers
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- SOHSUEBNGARM Damnern
- Avian Health Research Unit, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand
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- SASIPREEYAJAN Jiroj
- Avian Health Research Unit, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand
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- NITHIUTHAI Suwannee
- Veterinary Parasitology Unit, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand
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- CHANSIRIPORNCHAI Niwat
- Avian Health Research Unit, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand
書誌事項
- タイトル別名
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- The Efficacy of Artesunate, Chloroquine, Doxycycline, Primaquine and a Combination of Artesunate and Primaquine against Avian Malaria in Broilers
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抄録
The efficacy of 5 antimalarial drugs was evaluated on P. gallinaceum infected broilers. One hundred and forty-seven 19-day-old broilers were divided into 7 groups of 21 chicks each. Group 1 was the unmedicated, uninfected control. Groups 2–6 were infected and medicated with artesunate, chloroquine, doxycycline, primaquine and an artesunate-primaquine combination, respectively. Group 7 was the unmedicated, infected control. Infectivity, mortality, parasitemia, schizonts in tissues and body weight gain were monitored. The results revealed that the two most effective drugs for treating P. gallinaceum at the asexual erythrocyte stage were chloroquine and doxycycline. Tissue schizonts of P. gallinaceum in all the medicated groups were significantly fewer than the unmedicated, infected control (P<0.05). The mortality rate of all the medicated groups was significantly lower than the unmedicated, infected control (P<0.05).
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 76 (6), 813-817, 2014
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390282681406518656
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- NII論文ID
- 130003391285
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- NII書誌ID
- AA10796138
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- COI
- 1:STN:280:DC%2BC2cvlsVWrsQ%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 025617341
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- PubMed
- 24531829
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可