イヌの卵巣腫瘍における免疫組織化学的検索

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  • AKIHARA Yuko
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
  • SHIMOYAMA Yumiko
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
  • KAWASAKO Kazufumi
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
  • KOMINE Misa
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
  • HIRAYAMA Kazuko
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
  • KAGAWA Yumiko
    NORTH LABO
  • OMACHI Tetsuo
    PATHO LABO
  • MATSUDA Kazuya
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
  • OKAMOTO Minoru
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
  • KADOSAWA Tsuyoshi
    Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
  • TANIYAMA Hiroyuki
    Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University

書誌事項

タイトル別名
  • Immunohistochemical Evaluation of Canine Ovarian Tumors
  • Immunohistochemical evaluation of canine ovarian cysts

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抄録

Canine ovarian tumors (epithelial tumor, sex-cord stromal tumor, germ cell tumor) classifying into 9 histological types were examined immunohistochemically using placental alkaline phosphatase (PLAP), cytokeratin7 (CK7), desmin, S100, AE1/AE3, inhibin α, vimentin, and alfa feto-protein (AFP). The papillary and tubular types observed in epithelial tumors were immunoreactive for desmin and AE1/AE3. The papillary type was also immunoreactive for PLAP and CK7. The solid type, nest type, cord type, palisade type, cystic type and spindle type, which were observed in sex-cord stromal tumors, showed a positive immunoreaction for S100 but little or no positive immunoreaction for inhibin α with an exception of positive result in the palisade type. Most of the sex-cord stromal tumors were AE1/AE3-positive except for the palisade type. In the cobblestone type observed in germ cell tumors, only vimentin and AFP were positive. The present study elucidated the detailed histological and immunohistochemical characteristics of canine ovarian tumors.<br>

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