ブラジルの食肉目から分離された野外狂犬病ウイルスの系統学的解析

  • KOBAYASHI Yuki
    Nihon University Veterinary Research Center
  • INOUE Nana
    Nihon University Veterinary Research Center
  • SATO Go
    Nihon University Veterinary Research Center
  • ITOU Takuya
    Nihon University Veterinary Research Center
  • SANTOS Hamilton P.
    School of Veterinary Medicine, Maranhão State University, Campus I, Cidade Universitária Paulo VI
  • BRITO Cristina J. C.
    Faculty of Veterinary Medicine and Zootechny, University of São Paulo
  • GOMES Albério A. B.
    Department of Veterinary Medicine, Center of Health and Rural Technology, Federal University of Campina Grande
  • SANTOS Marli F. C.
    Center for Diagnostic and Veterinary Research, Goianian Rural and Fundiary Development Agency, Secretary of Agriculture and Livestock of the State of Goiás, Av. Anhanguera
  • SILVA Marlon V.
    Jorge Vaitsmann Municipal Institute, Av. Bartolomeu de Gusmão
  • MOTA Carla S.
    Faculty of Veterinary Medicine and Zootechny, University of São Paulo
  • ITO Fumio H.
    Faculty of Veterinary Medicine and Zootechny, University of São Paulo
  • SAKAI Takeo
    Nihon University Veterinary Research Center

書誌事項

タイトル別名
  • Phylogenetic Characterization of Rabies Virus Isolates from Carnivora in Brazil

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The incidence of canine rabies has been widely reported in Brazil, and new rabies virus (RV) variants, genetically similar to canine RV, have recently been isolated from foxes. In order to derive the epidemiological characteristics of Brazilian Carnivora RV, Brazilian RVs isolated from dogs, cats, and foxes were genetically analyzed. Brazilian Carnivora RV isolates were divided into 2 main lineages. The predominant lineage was found in dogs and cats, which included the Argentinean and Bolivian Carnivora RV isolates, and was extensively distributed throughout Brazil and surrounding countries. The other lineage consisted of three sublineages containing Brazilian dog and fox RV isolates, with the dog sublineages located on an internal branch of 2 fox sublineages, suggesting that RV transmission events might have occurred between foxes and dogs in the past. These results suggest that contact between dogs and wildlife has the potential to generate new rabies variants and that it is important to control RV infection cycles in both dogs and wildlife to prevent spread of rabies infection.<br>

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