Study on the Pathogenesis of Nephritis : (With Special Reference to Autoradiography) Part II Clinical Studies

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Following the previous research, the purpose of this present study is to find out some means overcoming the discrepancy between histological investigations of biopsy specimen obtained from nephritis patient and their clinical course. 3H-Thymidine was incubated with the biopsy specimen and autoradiogram was made in vitro. Proliferative change of kidneys was investigated as index of renal lesions on autoradiograph as described in the previous Part I and compared with renal function, immunological examination, biochemical study of serum as well as histological findings. The autoradiograph in vitro opened the possibility to evaluate the extent of renal lesions and furthermore clinical course of patients.

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