A Successful Case of the Prevention of Overwhelming Postsplenectomy Infection in a Girl with Hereditary Spherocytosis using Immediate Antibiotic Treatment

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  • Oki Yoko
    6th-year student,Nihon University School of Medicine
  • Shichino Hiroyuki
    Department of Pediatrics and Child Health, Nihon University School of Medicine
  • Yagasaki Hiroshi
    Department of Pediatrics and Child Health, Nihon University School of Medicine
  • Hirai Maiko
    Department of Pediatrics and Child Health, Nihon University School of Medicine
  • Shimozawa Katsuyoshi
    Department of Pediatrics and Child Health, Nihon University School of Medicine
  • Yonezawa Ryuta
    Department of Pediatrics and Child Health, Nihon University School of Medicine
  • Kato Maiko
    Department of Pediatrics and Child Health, Nihon University School of Medicine
  • Miyashita Michio
    Department of Pediatrics and Child Health, Nihon University School of Medicine
  • Chin Motoaki
    Department of Pediatrics and Child Health, Nihon University School of Medicine

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Other Title
  • 迅速 な治療開始で劇症化を防いだ脾摘後遺伝性球状赤血球症の 1 例
  • 症例報告 迅速な治療開始で劇症化を防いだ脾摘後遺伝性球状赤血球症の1例
  • ショウレイ ホウコク ジンソク ナ チリョウ カイシ デ ゲキショウカ オ フセイダ ヒテキゴ イデンセイ キュウジョウ セッケッキュウショウ ノ 1レイ

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Abstract

The spleen is an important part of the human immune system. After splenectomy, a patient can easily become infected and the symptoms can often be severe, which is known as overwhelming postsplenectomy infection (OPSI). We report a case of a girl who had two episodes of high fever twice following splenectomy. She was diagnosed with hereditary spherocytosis at forty days of age and underwent splenectomy when she was six years old. At both times, we assumed that she was infected with OPSI and immediately treated her with antibiotics. With the appropriate treatment, the symptoms did not worsen and she left hospital within a week. To prevent OPSI, it is necessary for the patient to understand the importance of prevention of infection, and prompt and appropriate treatment should be administered if the patient is suspected of having a bacterial infection.

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