発症後1年を経たTrigeminal sensory neuropathyが漢方薬で改善した1例

  • 廣谷 拓章
    東北大学大学院歯学研究科口腔病態外科学講座口腔外科学分野
  • 千葉 雅俊
    東北大学大学院歯学研究科口腔病態外科学講座口腔外科学分野
  • 越後 成志
    東北大学大学院歯学研究科口腔病態外科学講座口腔外科学分野

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  • A case of Trigeminal sensory neuropathy successfully treated with Kampo medicine started one year after onset
  • ハッショウ ゴ 1ネン オ ヘタ Trigeminal sensory neuropathy ガ カンポウヤク デ カイゼン シタ 1レイ

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We report a case of trigeminal sensory neuropathy that was thought to have occurred with cold stimulation, and was successfully treated with Kampo medicine started one year after onset. A 37-year-old male noted heat sensation in the right infraorbital region and upper lip that developed after exposure to cold wind at midnight on February X-1, followed by hypoesthesia and dysestesia in the same area and the right gingiva of the maxilla. There were no other significant abnormalities on ophthalmic, otorhinolaryngological, and neurological examinations. He was referred to our department on February X because neuropathy persisted despite taking a vitamin B12 preparation and undergoing root canal treatment of the right canine of the maxilla which was performed because he had felt swollenness of the gingiva and unpleasant sensation during mastication. He was diagnosed as having neuropathy of the second branch of the right trigeminal nerve because he presented with hypoesthesia and dysestesia in distribution of the right infraorbital nerve. Contrast-enhanced magnetic resonance imaging of the craniofacial region showed no abnormalities. He showed some improvement with Goreisan and stopped taking it after 3 months because he was no longer troubled by the neuropathy, which made satisfactory progress thereafter. The cause of trigeminal sensory neuropathy could not be identified, however, cold stimulation might have served as the trigger. Improvement in neuropathy, when the treatment is started after an extended period after onset, is usually difficult. However, Kampo medicine produces a good response to it in some cases, and we consider that Kampo medicine may be a useful option for the treatment of neuropathy.

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