A case of myoepithelial carcinoma arising in the mucosa of the lower lip

  • OHSAKO Toshimitsu
    Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • OMURA Ken
    Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • HARADA Hiroyuki
    Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • KAYAMORI Kou
    Diagnostic Oral pathology, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University

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Other Title
  • 下唇粘膜部に発生した筋上皮癌の1例
  • カシン ネンマクブ ニ ハッセイ シタ キン ジョウヒガン ノ 1レイ

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Myoepithelial carcinoma (MC) is an extremely rare tumor accounting for approximately 0.2% of all salivary gland tumors. It is often difficult to diagnose MC because the tumor cells of MC show a wide variety of morphologies. We report a case of MC arising in the lower lip.<br>A 54-year-old male patient was referred to our department for evaluation of a mass in the right lower lip. Physical examination revealed a submucosal mass lesion measuring 2.5 × 2.0 cm with a well-defined border. It was elastic soft and ovate in shape. There was no palpable cervical lymphadenopathy. Biopsy of the mass suggested epithelial malignant tumor. He underwent local excision of the tumor and the resulting surgical defect was covered by a split-thickness skin graft. Postoperative histopathologic examination confirmed the diagnosis of MC with neuroendocrine differentiation.<br>The patient is being followed up and shows no evidence of local recurrence or lymph node or distant metastasis of the tumor 24 months after surgery.

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