A case of essential hypernatremia presumably caused by partial diabetes insipidus, upward resetting of osmostat and hypodipsia.
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- INOUE Minoru
- The Second Department of Internal Medicine, Tohoku University School of Medicine
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- KIMURA Tokihisa
- The Second Department of Internal Medicine, Tohoku University School of Medicine
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- MATSUI Kuniaki
- The Second Department of Internal Medicine, Tohoku University School of Medicine
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- OTA Kozo
- The Second Department of Internal Medicine, Tohoku University School of Medicine
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- IITAKE Kazuhiro
- The Second Department of Internal Medicine, Tohoku University School of Medicine
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- SHOJI Masaru
- The Second Department of Internal Medicine, Tohoku University School of Medicine
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- YOSHINAGA Kaoru
- The Second Department of Internal Medicine, Tohoku University School of Medicine
Bibliographic Information
- Other Title
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- 不完全型尿崩症，ｏｓｍｏｓｔａｔの上昇および渇感の低下により生じた本態性高Ｎａ血症の１例
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Description
本態性高Na血症の1例について,その血中ADHの動態を検討したので報告する.症例は68才,女性.昭和48年当科にて不完全型尿崩症の診断を受けcarbamazepineの投与を受けていた.昭和57年12月10日,軽度の意識障害のため当科外来を受診.著明な高Na血症を指摘され入院となつた.入院時渇感は低下し,血中および尿中ADHは,血漿浸透圧に比して低値であつた. Carter-Robbins testでは, ADH分泌の浸透圧閾値の高値へのresettingが認められた.以上の結果より,本症例は,渇感の低下, osmoreceptorの高値へのresettingおよびADHの産生低下により生じた本態性高Na血症と考えられた.
Journal
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- Nihon Naika Gakkai Zasshi
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Nihon Naika Gakkai Zasshi 74 (12), 1699-1703, 1985
The Japanese Society of Internal Medicine
