イオン交換樹脂服用時に於けるアミノ酸及び塩類の吸收に關する實驗的研究

吉田 守人

doi:10.2169/naika.43.883

イオン交換樹脂服用時に於けるアミノ酸及び塩類の吸收に關する實驗的研究

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吉田守人

北海道大學第三内科

書誌事項

タイトル別名

THE EXPERIMENTAL STUDIES OF THE ABSORPTION OF AMINO-ACID AND SALTS WHEN ION EXCHANGE RESINS ARE USED
イオンコウカンジュシフクヨウジニオケルアミノサンオヨビエンルイノキュウシュウニカンスルジッケンテキケンキュウ

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On high efficient Cation Exchange Resins, AmRIR IR 120 and AmR IRC 50 and Anion Exchange Resin AmRIR IR 4 which are now most widely used in Japan. I conducted experiments in vitro and in vivo to see if they will absorb amino-acid, the most important nutritive substance for a human body, when they are taken or whether or not they will be hindered from absorbed it. As a result of the experiments, I knew part of basic amino-acids are absorbed and excreted by Cation Exchange Resins. Furthermore administering H-type and NH₄-type of AmRIR 120 and AmR IRC 50 to rats, I observed these facts: 1) The rat's weight did not undergo a remarkable change and the urine increased in quantity. 2) The excretion of Na and K in the urine remarkably increased, while that of Na and K in the feces decreased. 3) The sum of excretion of Na and K in the feces and urine showed an increase in proportion to its contrast. 4) The excretion of N decreased in H-type and increased in NH₄-type.