A Japanese Case of Familial Mediterranean Fever with Onset in the Thirties

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  • Sawada Jun
    Division of Cardiology, Respirology and Neurology, Department of Internal Medicine, Asahikawa Medical University
  • Asanome Asuka
    Division of Cardiology, Respirology and Neurology, Department of Internal Medicine, Asahikawa Medical University
  • Endo Hisako
    Division of Cardiology, Respirology and Neurology, Department of Internal Medicine, Asahikawa Medical University
  • Saito Tsukasa
    Division of Cardiology, Respirology and Neurology, Department of Internal Medicine, Asahikawa Medical University
  • Katayama Takayuki
    Division of Cardiology, Respirology and Neurology, Department of Internal Medicine, Asahikawa Medical University
  • Hasebe Naoyuki
    Division of Cardiology, Respirology and Neurology, Department of Internal Medicine, Asahikawa Medical University
  • Migita Kiyoshi
    Department of Rheumatology, National Hospital Organization Nagasaki Medical Center
  • Ida Hiroaki
    Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine

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Other Title
  • 30代で発症した家族性地中海熱の1例
  • 今月の症例 30代で発症した家族性地中海熱の1例
  • コンゲツ ノ ショウレイ 30ダイ デ ハッショウ シタ カゾクセイ チチュウカイ ネツ ノ 1レイ

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症例は53歳，男性．35歳頃から月に1日程度37℃台の発熱と胸背部や腹部，関節の疼痛が出現し，その後症状の出現頻度が週に1日程度に増加した．身体所見上明らかな異常を認めず，血液検査では軽度の炎症反応の上昇を認めるのみで，画像検査でも異常を認めなかった．MEFV遺伝子の変異を認めたことから，家族性地中海熱（FMF）と診断した．成人の周期性発熱の原因として，FMFの可能性を考慮する必要がある．<br>

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