Ｓａｌｍｏｎｅｌｌａ食菌Ｕ９３７細胞表面抗原の動態に関する研究

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  • Modulation of the surface antigens of Salmonella-phagocytized U937 cells.
  • Salmonella ショクキン U937 サイボウ ヒョウメン コウゲン ノ

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In this study, modulation of the surface antigens of Salmonella enteritidis-phagocytized U937 cells and morphology of the bacteria in these cells were analyzed by the indirect immunofluorescence technique. The results are as follows: (1) Morphological studies revealed that the bacteria phagocytized by the U937 cells were transformed to a small coccoid form. (2) The expression of CD14 antigen was observed 24 to 48h after phagocytosis. (3) The levels of CD11b and CD23 antigens were clearly enhanced 48h after phagocytosis. (4) No modulation of HLA-class II (DR, DQ and DP) antigens was observed after phagocytosis.

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