A Case of Anti-SRP Positive Immune-mediated Necrotizing Myopathy Treated Effectively with Combined Immunotherapy
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- Yamashita Yuya
- Post-graduate Education Center of Tokushima University Hospital
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- Yamazaki Hiroki
- Department of Neurology, Tokushima University Hospital
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- Matsui Naoko
- Department of Neurology, Tokushima University Hospital
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- Miyazaki Yoshimichi
- Department of Neurology, Tokushima University Hospital
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- Tsukamoto Ai
- Department of Neurology, Tokushima University Hospital
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- Nishino Ichizo
- Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry
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- Suzuki Shigeaki
- Department of Neurology, Keio University School of Medicine
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- Nishida Yoshihiko
- Department of Neurology, Itsuki Hospital
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- Nodera Hiroyuki
- Department of Neurology, Tokushima University Hospital
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- Izumi Yuishin
- Department of Neurology, Tokushima University Hospital
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- Kaji Ryuji
- Department of Neurology, Tokushima University Hospital
Bibliographic Information
- Other Title
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- 複合的免疫治療が奏効した抗SRP抗体陽性壊死性ミオパチーの1例
- 今月の症例 複合的免疫治療が奏効した抗SRP抗体陽性壊死性ミオパチーの1例
- コンゲツ ノ ショウレイ フクゴウテキ メンエキ チリョウ ガ ソウコウ シタ コウSRP コウタイ ヨウセイ エシセイ ミオパチー ノ 1レイ
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Abstract
<p>症例は60歳代，男性．全身倦怠感，四肢脱力を主訴に受診．筋炎としステロイド単独で治療を開始したが，反応性は乏しく，筋病理・抗体検査にて抗SRP抗体陽性壊死性ミオパチー（anti-signal recognition particle immune-mediated necrotizing myopathy：anti-SRP iNM）と診断し，免疫グロブリン大量静注療法，免疫抑制薬を併用したところ，症状の改善を得た．積極的に自己抗体の測定を行うことが壊死性ミオパチー（immune-mediated necrotizing myopathy：iNM）の早期診断・治療に重要である．</p>
Journal
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- Nihon Naika Gakkai Zasshi
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Nihon Naika Gakkai Zasshi 105 (8), 1443-1450, 2016
The Japanese Society of Internal Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390282681425704832
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- NII Article ID
- 130005950164
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- NII Book ID
- AN00195836
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- ISSN
- 18832083
- 00215384
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- NDL BIB ID
- 027613731
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed