?EＢｉｆｉｄｏｂａｃｔｅｒｉｕｍ?F菌体成分の腸管吸収に関する研究　Ｉ　　無菌マウスおよび普通マウスにおける〔?Q３?RＨ〕ロイシン標識?EＢｉｆｉｄｏｂａｃｔｅｒｉｕｍ　ｂｉｆｉｄｕｍ?Fおよびその菌体抽出液の腸管からの吸収

DOI Web Site

書誌事項

タイトル別名
  • Studies on Intestinal Absorption of Cellular Constituents of <i>Bifidobacterium</i>
  • Bifidobacterium キンタイ セイブン ノ チョウカン キュウシュ
  • 第1報 無菌マウスおよび普通マウスにおける〔<sup>3</sup>H〕ロイシン標識<i>Bifidobacterium bifidum</i>およびその菌体抽出液の腸管からの吸収

この論文をさがす

説明

An experiment was carried out to determine whether the cellular amino acids and proteins of Bifidobacterium bifidum harbored in the intestinal tract could be utilized by the host. In it germfree and conventional mice were administered orally with live cells of B. bifidum labelled with [3H] leucine, as well as heat-killed cells and cytoplasmic extracts derived therefrom. Radioactivity in the serum was followed in these animals over a 7-day experimental period.<br>Four different types of samples were prepared from radiolabelled B. bifidum for administration by the aid of a gastric tube. They were (i) suspension of live cells, (ii) suspension of heat-killed cells, (iii) cytoplasmic extract, and (iv) heated cytoplasmic extract. In conventional mice, radioactivity was recovered from the serum at appreciable rates within 1 hour after administration, reaching a maximal level at the 4th to 8th hour with a subsequent gradual decrease. The recovery rate in these animals was dependent on the type of samples. It was the highest in mice administered with sample (ii) and rather low in mice administered with sample (i). Radioactivity was the lowest in mice administered with samples (iii) and (iv). On the other hand, the recovery rate was higher in germfree mice administered with sample (i) than in those administered with sample (ii).<br>These results led to the following conclusions. When mice were administered orally with live cells, heat-killed cells, or cytoplasmic extracts of B. bifidum, amino acids and proteins contained in this organism were absorbed from their intestinal tract and utilized efficiently. The efficiency of their intestinal absorption depended significantly on the type of cells or extract administered and on the state of the intestinal flora.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ