書誌事項
- タイトル別名
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- Requirement of cyclic 3', 5'-monophosphate in the production of a permeability increasing factor by Vibrio cholerae.
- コレラキン ノ モウサイケッカン トウカセイ コウシン インシ サンセイ ニ
この論文をさがす
抄録
Enterotoxin production by cAMP-deficient mutants of Vibrio cholerae was investigated by the latex agglutination test, CHO cell elongation system, and permeability increasing test. It was revealed that two kinds of permeability-increasing factors were produced by V. cholerae E2 and its cAMP-deficient mutant E2751. They were cholera toxin (CT) and an unknown permeability-increasing factor (PF). PF was separated from CT by DEAE-Sephacel column chromatograhy. Antiserum was prepared against partially purified PF separated by DEAE-Sephacel chromatography and used for the neutralization tests. Neutralization tests with anti CT antiserum and anti PF antiserum showed that CT and PF were entirely different immunplogically. We showed also that though cAMP is not essential for production of CT, it is required for production of this newly found PF.
収録刊行物
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- 日本細菌学雑誌
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日本細菌学雑誌 41 (3), 603-610, 1986
日本細菌学会
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詳細情報 詳細情報について
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- CRID
- 1390282681427147264
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- NII論文ID
- 130001385732
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- NII書誌ID
- AN00189800
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- ISSN
- 18824110
- 00214930
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- NDL書誌ID
- 3086023
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- PubMed
- 3018312
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可