Measurements of Right Ventricular Pressure and Plasma ANP and NT-proBNP Levels in a Dog with Tricuspid Valve Regurgitation

  • HORI Yasutomo
    Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University
  • MURAKAMI Haruka
    Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University
  • SATO Chihaya
    Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University
  • NAKAGAWA Akina
    Aleph Animal Hospital
  • MIURA Hiroshi
    Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University
  • KIKUCHI Motohiro
    Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University
  • OHNAMI Youji
    Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University

Bibliographic Information

Other Title
  • 三尖弁閉鎖不全症犬において右心内圧と血中ANPならびにNT-proBNP濃度を測定した1例
  • 症例報告 三尖弁閉鎖不全症犬において右心内圧と血中ANPならびにNT-proBNP濃度を測定した1例
  • ショウレイ ホウコク サン センベン ヘイサ フゼンショウケン ニ オイテ ウシン ナイアツ ト ケッチュウ ANP ナラビニ NT proBNP ノウド オ ソクテイ シタ 1レイ

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Description

A 13-year-old female Beagles dog was referred with a history of abdominal enlargement and dyspnea. Thoracic radiograph revealed cardiac enlargement. Echocardiograph revealed tricuspid valve regurgitation. Although right atrial pressure was normal, right ventricular pressure was elevated (systolic/end-diastolic; 69/5.0 mmHg). Similarly, although plasma ANP was normal, plasma NT-proBNP was elevated to 1,583 pmol/L. The following medications were prescribed: enalapril, torasemide, and methyldigoxin. After 30 days of treatment, clinical signs and right ventricular pressure was decreased (20/-2.3 mmHg). The plasma NT-proBNP had decreased to 1,245 pmol/ml. These results suggest that elevated right ventricular pressure induced in an increase in plasma NT-proBNP levels.

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