書誌事項
- タイトル別名
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- Water Molecule Structure on Material Interface Related to Protein Adsorption
- タンパク質吸着に及ぼす材料界面の水分子構造 : 和周波発生分光法による解析から
- タンパクシツ キュウチャク ニ オヨボス ザイリョウ カイメン ノ ミズブンシ コウゾウ : ワシュウハ ハッセイ ブンコウホウ ニ ヨル カイセキ カラ
- —和周波発生分光法による解析から—
- Study on Sum-Frequency Generation Spectroscopy (SFG)
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抄録
Adsorbed proteins initiate the undesirable phenomena like blood coagulation and immune response, and lead to the negative effects on human body and function of biodevices. Thus, the suppression of protein adsorption is essential property for biomaterials. Therefore, interfacial water molecules may play a key role on protein adsorption. In this study, various types of surface; hydrophobic, hydrophilic, anionic, cationic and zeitterionic were prepared by high-density polymer brush having different molecular structure. The amount of adsorbed negatively and positively charged protein was analyzed by quartz crystal microbalance (QCM) method to investigate the protein adsorption on polymer brush surfaces quantitatively. Structure of interfacial water at the interface between polymer brush and water media was investigated using sum-frequency generation (SFG) spectroscopy. From the quantitative comparison with protein adsorption and structure of interfacial water molecule of each polymer brush, it is concluded that the interfacial water molecules, which form strong hydrogen bonding is a strong relation to the suppression of protein adsorption.
収録刊行物
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- 表面科学
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表面科学 35 (9), 492-497, 2014
公益社団法人 日本表面科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681435085824
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- NII論文ID
- 130004691165
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- NII書誌ID
- AN00334149
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- ISSN
- 18814743
- 03885321
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- NDL書誌ID
- 025800498
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可
