ニワトリヒナの摂食行動に及ぼすニューロペプチドYとクロニジンの脳室内投与の効果

DOI 日本農学文献記事索引 Web Site Web Site 被引用文献2件 参考文献17件
  • 豊後 貴嗣
    九州大学大学院生物資源環境科学研究科
  • 崔 洋豪
    Department of Nutritional Science, Faculty of Medicine, University of Toronto
  • DENBOW D. Michael
    Department of Animal and Poultry Science, Virginia Polytechnic Institute and State University
  • 下條 雅敬
    九州大学大学院生物資源環境科学研究科
  • 増田 泰久
    九州大学大学院生物資源環境科学研究科
  • 古瀬 充宏
    九州大学大学院生物資源環境科学研究科

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タイトル別名
  • Intracerebroventricularly Administrered Neuropeptide Y and Clonidine: Effects on Feeding Behavior in the Neonatal Chick

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To clarify the relationship between neuropeptide Y (NPY) and the α2-adrenergic system on ingestive behavior of the young chick, NPY receptor and α2-adrenoceptor were stimulated by intracerebroventricular injection of NPY and clonidine (CLON), α2-receptor agonist, respectively. Central injection of NPY (1, 2.5 or 5μg) significantly increased food intake in a dose-dependent manner in Experiment 1. No additive or synergistic effect was observed when NPY (1μg) and CLON (50ng) were co-administered. However, a significant interaction between NPY (2.5μg) and CLON (50ng) was observed in food intake, implying that an enhanced food intake by NPY was attenuated by co-injection with CLON. These results indicate that α2-adrenoceptors and NPY may interact and regulate food intake within the central nervous system in the young chick, depending their concentrations.

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