Comparison of Blood Removal Catheters for Extracorporeal Circulation in Low Body Weight Animals

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  • HORI Yasutomo
    Laboratory of Small Animal Internal Medicine II, School of Veterinary Medicine, Kitasato University
  • SAITOH Ryuta
    Laboratory of Small Animal Internal Medicine II, School of Veterinary Medicine, Kitasato University
  • TOUEI Daisuke
    Laboratory of Small Animal Internal Medicine II, School of Veterinary Medicine, Kitasato University
  • KANAI Kazutaka
    Laboratory of Small Animal Internal Medicine I, School of Veterinary Medicine, Kitasato University
  • CHIKAZAWA Seishiro
    Laboratory of Small Animal Internal Medicine II, School of Veterinary Medicine, Kitasato University
  • HOSHI Fumio
    Laboratory of Small Animal Internal Medicine II, School of Veterinary Medicine, Kitasato University
  • ITOH Naoyuki
    Laboratory of Small Animal Internal Medicine I, School of Veterinary Medicine, Kitasato University
  • HIGUCHI Sei-ichi
    Laboratory of Small Animal Internal Medicine I, School of Veterinary Medicine, Kitasato University

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Other Title
  • 低体重動物の体外循環に向けた脱血カテーテルの基礎的検討
  • テイタイジュウ ドウブツ ノ タイガイ ジュンカン ニ ムケタ ダツケツ カテーテル ノ キソテキ ケントウ

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Perfusion rate under extracorporeal circulation may be low-flow rate in low body weight animals, which can sometimes cause a serious problem. Our aim of the present study was to investigate the shapes of blood removal catheters for extracorporeal circulation. In a pilot study, flow rates of several blood removal and sending catheters were recorded in water tank. Flow rate was consistent with the width of the blood removal catheter and significantly increased. In contrast, it opposed to the length of the catheter and significantly decreased. Flow rate in blood removal catheters with side-hole was significantly higher than in blood removal catheters without side-hole. In vivo study, to compare the flow rate of blood removal catheters between side-hole and end-hole, Japanese white rabbits (n=5) were used under extracorporeal circulation. Compared to the end-hole catheters, side-hole catheters significantly elevated flow rate, systemic arterial pressure, PaO2, and plasma HCO3- concentration. Our results suggested that blood removal catheters with side-hole may provide the safety under extracorporeal circulation in low body weight animals.

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