The in vitro effect of macrolide antibiotics and lincomycin on Streptococcus sp., the etiological agent of streptococcal infection in yellowtail, Seriola quinqueradiata.

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Other Title
  • ブリ連鎖球菌Streptococcus sp.に対するマクロライド系抗生物質およびリンコマイシンの試験管内作用
  • ブリ レンサ キュウキンStreptococcus sp.ニ タイスル マクロ

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Abstract

In vitro efficacy of five antibiotics were tested against Streptococcus sp., the causative agent of streptococcal infection in yellowtail. Erythromycin and spiramycin are currentry used to control the disease and had 0.0125-0.39μg/ml minimum inhibitory concentration (MIC) and 0.2-1.56μg/ml MIC respectively. Josamycin, tylosin and lincomycin currentry not used, had respectively 0.1-0.39μg/ml, 0.1-1.56 μg/, ml 0.0125-0.1μg/ml MIC.<BR>The time to death kinetics using the five antibiotics were studied. Drug resistance to the antibiotics developed after 10 serial passages in the presence of the antibiotic.

Journal

  • Fish Pathology

    Fish Pathology 20 (4), 453-457, 1985

    The Japanese Society of Fish Pathology

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