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The selective inhibitors against SV40-transformed cells. selective inhibition of SV40-transformed cell growth by diketopiperazines.
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- MUNEKATA Masanobu
- Laboratory of Microbiology, Department of Agricultural Chemistry, The University of Tokyo Research and Development Laboratories, Sapporo Breweries Ltd.
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- TAMURA Gakuzo
- Laboratory of Microbiology, Department of Agricultural Chemistry, The University of Tokyo
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Description
Two diketopiperazines have been isolated from the culture broth of a soil Actinomycetales, Streptomyces sp. strain ML1532. They were cyclo(L-Val-L-Pro) and cyclo(L-Tyr-L-Pro). The selective cytotoxicity of cyclo(L-Tyr-L-Pro) was slightly higher than that of cyclo(L-Val-L-Pro) against SV40-transformed cells.
Journal
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- Agricultural and Biological Chemistry
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Agricultural and Biological Chemistry 45 (11), 2613-2618, 1981
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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Keywords
Details 詳細情報について
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- CRID
- 1390282681440405376
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- NII Article ID
- 130000028740
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- COI
- 1:CAS:528:DyaL38XltVKhsA%3D%3D
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- ISSN
- 18811280
- 00021369
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed