Antimicrobial Activity of 3-Phenylimidazolidine-2, 4-diones and Related Compounds

FUJINAMI Akira, TOTTORI Nobumasa, KATO Toshiro, KAMEDA Nobuyuki

doi:10.1080/00021369.1972.10860439

Description

The structure-activity relationships of 3-(3', 5'-dichlorophenyl) imidazolidine-2, 4-dione derivatives were investigated by the agar dilution method using Sclerotinia sclerotiorrun as a test microbe. Several compounds were tested for antimicrobial spectrum in vitro with other pathogenic microbes and for foliage protective activity in green house tests with rice sheath blight, rice brown spot, damping-off of cucumber and kidney bean stem rot. It was found that the antimicrobial activity was enhanced when the 1-position of imidazolidine ring was substituted by an alkyl group but was reduced when the 5-position was substituted by alkyl groups. Generally, 3-(3', 5'-dichlorophenyl) imidazolidine-2, 4-dione derivatives were active against Sclerotiniaceae, Corticiaceae, Dematiaceae, Polvstigmataceae or Pleosporaceae. In green house tests, some of these compounds showed high protective activity against rice sheath blight, rice brown spot, damping-off of cucumber and kidney bean stem rot. Results of the green house tests on the above mentioned diseases correlate well with those of in vitro tests except in the case of kidney bean stem rot.

Journal

Agricultural and Biological Chemistry

Agricultural and Biological Chemistry 36 (9), 1623-1630, 1972

Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

Details 詳細情報について

CRID: 1390282681445229568

NII Article ID: 130003524012

DOI: 10.1271/bbb1961.36.1623; 10.1080/00021369.1972.10860439

COI: 1:CAS:528:DyaE3sXmslCksA%3D%3D

ISSN: 18811280; 00021369

Text Lang: en

Data Source

JaLC
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CiNii Articles
OpenAIRE

Abstract License Flag: Disallowed

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