A New Toxic Substance, Teleocidin, Produced by Strepsomyces

  • TAKASHIMA Matao
    Tokyo Research Laboratory, Fujisawa Pharmaceutical Industries, Ltd.
  • SAKAI Heiichi
    Tokyo Research Laboratory, Fujisawa Pharmaceutical Industries, Ltd.
  • MORI Rinpei
    Department of Agricultural Chemistry, University of Tokyo
  • ARIMA Kei
    Department of Agricultural Chemistry, University of Tokyo

書誌事項

タイトル別名
  • A New Toxic Substance, Teleocidin, Produced by <I>Strepsomyces</I>
  • A new toxic substance, teleocidin, produced by Streptomyces. Part IV. Degradative studies of hydroteleocidin B and teleocidic anhydride
  • Part IV. Degradative Studies of Hydroteleocidin B and Teleocidic Anhydride

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説明

A new toxic substance, Teleocidin B, was isolated from the mycellium of aSStreptomyces. The chemical structure of this compound was studied using its crystalline hydrogenated derivative (Hydroteleocidin B). As the results of these studies, a new acid anhydride named teleocidic anhydride was isolated by the oxidative degradation and it was postulated as 3, 6-dimethyl-6-amyl-1-cyclohexene-1, 2-dicarboxylic anhydride. The partial structure of Hydroteleocidin B was also discussed in this paper.

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