Effects of Chemical Modification of Carboxyl Groups in the Hemolytic Lectin CEL-3 on Its Hemolytic and Carbohydrate-Binding Activities

DOI Web Site Web Site PubMed 参考文献16件 オープンアクセス
  • KUWAHARA Hiromiki
    Department of Applied Chemistry, Faculty of Engineering, Nagasaki University
  • FUNADA Takako
    Department of Applied Chemistry, Faculty of Engineering, Nagasaki University
  • HATAKEYAMA Tomomitsu
    Department of Applied Chemistry, Faculty of Engineering, Nagasaki University
  • AOYAGI Haruhiko
    Department of Applied Chemistry, Faculty of Engineering, Nagasaki University

書誌事項

タイトル別名
  • Effects of Chemical Modification of Carboxyl Groups in the Hemolytic Lectin CEL-III on Its Hemolytic and Carbohydrate-Binding Activities.

この論文をさがす

説明

Effects of chemical modification of carboxyl groups in the hemolytic lectin CEL-III on its activities were investigated. When carboxyl groups were modified with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and glycine methyl ester, hemolytic activity of CEL-III decreased as the EDC concentration increased, accompanied by reduction of oligomerization ability and hemagglutinating activity. However, binding ability of CEL-III for immobilized lactose was retained fairly well after modification, suggesting that one of two carbohydrate-binding sites might be responsible for such inactivation of CEL-III.<br>

収録刊行物

参考文献 (16)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ