Suppression by Water Extracts of Sophora Plants of Sucrose-induced Hyperglycemia in Rats and Inhibition of Intestinal Disaccharidases In Vitro.

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  • SHI Hai-Chao
    Department of Applied Biological Chemistry, Osaka Prefecture University
  • HUANG Qu-Yun
    The State-Expense Medical Service, The Second Hospital of Fuzhou
  • YAMAJI Ryoichi
    Department of Applied Biological Chemistry, Osaka Prefecture University
  • INUI Hiroshi
    Department of Applied Biological Chemistry, Osaka Prefecture University
  • FUJITA Tomoyuki
    Department of Applied Biological Chemistry, Osaka Prefecture University
  • MIYATAKE Kazutaka
    Department of Applied Biological Chemistry, Osaka Prefecture University
  • NAKANO Yoshihisa
    Department of Applied Biological Chemistry, Osaka Prefecture University
  • TADA Toshiji
    Research Institute for Advanced Science and Technology, Osaka Prefecture University
  • NISHIMURA Keiichiro
    Research Institute for Advanced Science and Technology, Osaka Prefecture University

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  • Suppression by Water Extracts of Sophor
  • Suppression by Water Extracts of<i>Sophora</i>Plants of Sucrose-induced Hyperglycemia in Rats and Inhibition of Intestinal Disaccharidases<i>In Vitro</i>

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Partially purified hot-water extracts of the roots of plants of the Sophora family suppressed the increase in blood glucose concentration of rats in the oral sugar tolerance test. The extracts also inhibited rat intestinal sucrase and maltase. The most potent sample was about 15 times more active than catechin, a positive control, in these experiments.<br>

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