Unusual Transcription Regulation of the<i>niaD</i>Gene under Anaerobic Conditions Supporting Fungal Ammonia Fermentation

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  • TAKASAKI Kazuto
    Institute of Applied Biochemistry, University of Tsukuba
  • SHOUN Hirofumi
    Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  • NAKAMURA Akira
    Institute of Applied Biochemistry, University of Tsukuba
  • HOSHINO Takayuki
    Institute of Applied Biochemistry, University of Tsukuba
  • TAKAYA Naoki
    Institute of Applied Biochemistry, University of Tsukuba

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タイトル別名
  • Unusual Transcription Regulation of the niaD Gene under Anaerobic Conditions Supporting Fungal Ammonia Fermentation

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説明

The niaD gene of the fungus Aspergillus nidulans encodes an assimilatory nitrate reductase and exogenous ammonium represses its expression. Under anoxic conditions, however, A. nidulans expressed niaD even in the presence of ammonium and used the gene product for dissimilatory nitrate reduction (ammonia fermentation). This transcription regulation mechanism under anaerobiosis is critical for the fungus to ferment ammonium.

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