Functional Conservation between Fission Yeast<i>moc1/sds23</i>and Its Two Orthologs, Budding Yeast<i>SDS23</i>and<i>SDS24</i>, and Phenotypic Differences in Their Disruptants
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- GOLDAR Md. Muniruzzaman
- Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University
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- NISHIE Toshikazu
- Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University
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- ISHIKURA Yasue
- Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University
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- FUKUDA Toshifumi
- Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University
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- TAKEGAWA Kaoru
- Department of Life Sciences, Faculty of Agriculture, Kagawa University
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- KAWAMUKAI Makoto
- Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University
書誌事項
- タイトル別名
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- Functional Conservation between Fission Yeast moc1/sds23 and Its Two Orthologs, Budding Yeast SDS23 and SDS24, and Phenotypic Differences in Their Disruptants
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説明
The moc1/sds23 gene was isolated to induce sexual development of a sterile strain due to overexpression of adenylate cyclase in Schizosaccharomyces pombe. Here, we studied the functional conservation between moc1/sds23 and its two orthologs SDS23 and SDS24 in Saccharomyces cerevisiae. We observed that the temperature sensitivity, salt tolerance, cell morphology, and sterility of the Δmoc1 mutant in S. pombe were recovered by expressing either S. cerevisiae SDS23 or SDS24. We found that deletion of both SDS23 and SDS24 resulted in the production of a large vacuole that was reversed by the expression of S. pombe moc1/sds23. In these ways we found that S. pombe Moc1/Sds23 and S. cerevisiae SDS23p or SDS24p are functional homologs. In addition we found that the Δsds23 Δsds24 diploid strain reduces cell separation in forming pseudohyphal-like growth in S. cerevisiae. Thus S. pombe moc1/sds23 and S. cerevisiae SDS23 or SDS24 are interchangeable with each other, but their disruptants are phenotypically dissimilar.
収録刊行物
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- Ｂｉｏｓｃｉｅｎｃｅ， Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， ａｎｄ Ｂｉｏｃｈｅｍｉｓｔｒｙ
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Ｂｉｏｓｃｉｅｎｃｅ， Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， ａｎｄ Ｂｉｏｃｈｅｍｉｓｔｒｙ 69 (7), 1422-1426, 2005
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681451044992
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- NII論文ID
- 10016644222
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 7378597
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- PubMed
- 16041152
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- IRDB
- NDLサーチ
- Crossref
- PubMed
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- 抄録ライセンスフラグ
- 使用不可
