Role of Ornithine in the<i>N</i>-Acetylglutamate Turnover in the Liver of Rats
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- HAYASE Kazutoshi
- Department of Home Economics, Aichi University of Education
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- YOSHIDA Akira
- Department of Food and Nutritional Sciences, Nagoya Bunri Junior College
書誌事項
- タイトル別名
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- Role of Ornithine in the N-Acetylglutamate Turnover in the Liver of Rats.
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説明
We determined whether the synthesis and degradation of N-acetylglutamate would regulate urea synthesis when the ornithine status was manipulated. Experiments were done on two groups of rats, each being treated with ornithine or saline (control). The plasma concentration of urea and the liver concentration of N-acetylglutamate in rats given ornithine were each significantly higher than in the control rats. Compared with the control rats, the liver N-acetylglutamate degradation was significantly lower in those rats treated with ornithine. Treatment of the rats with ornithine did not affect N-acetylglutamate synthesis in the liver. An inverse correlation between the liver N-acetylglutamate degradation and liver concentration of N-acetylglutamate was found. These results suggest that the lower degradation of N-acetylglutamate in the ornithine treatment group would be likely to increase the hepatic concentration of this compound and stimulate urea synthesis.<br>
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 63 (3), 506-509, 1999
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681451367424
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- NII論文ID
- 110002679507
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- NII書誌ID
- AA10824164
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- COI
- 1:STN:280:DyaK1M3ktlOhtg%3D%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 4691333
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- PubMed
- 10227137
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可