Anti-stress and Anti-fatigue Effects of Fermented Rice Bran.

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  • KIM Kyung Mi
    School of Food Biotechnology, Woosong University
  • YU Kwang Won
    Department of Kimchi and Food Science, Chongju National College of Scince and Technology
  • KANG Duk Ho
    Department of Social Physical Education, Soonchunhyang University
  • KOH Jong Ho
    Nel Biotech Co., LTD.
  • HONG Bum Shik
    Graduate School of Biotechnology, Korea University
  • SUH Hyung Joo
    Department of Food and Nutrition, College of Health Sciences, Korea University

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Abstract

The anti-stress and anti-fatigue effects on rats and mice of a hot water extract of rice bran fermented with Saccharomyces cerevisae IFO 2346 were investigated. Oral administration (1 g/kg/day) of the hot water extract of fermented rice bran (FRB) inhibited major changes in the weight of the adrenal, thymus, spleen and thyroid, showing an anti-stress effect. The hot water extract of FRB also inhibited increases in the GPT and LDH activity, cholesterol and glucose in the serum. The administration (1 g/kg/day) for 2 weeks significantly prolonged the swimming time, resulting in an increase in the anti-fatigue effect. It is considered from these results that FRB had anti-stress and anti-fatigue effects.

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