Synthesis and Biological Activity of<i>N</i>-Acyl<i>O</i>-Indolylalkyl Ethanolamines

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  • JIANG Shaoliang
    College of Pharmaceutical Science, Zhejiang University of Technology
  • GAO Jianrong
    State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology
  • HAN Liang
    State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology

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  • Synthesis and Biological Activity of N-Acyl O-Indolylalkyl Ethanolamines

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The plant-growth regulators, indole-3-carboxylic acids, were introduced into N-acyl ethanolamines, and a series of N-acyl O-indolylalkyl ethanolamines were prepared. Their biological activities to regulate rape hypocotyl elongation, cucumber cotyledon expansion and common wheat coleoptile growth were tested. The results indicate that the title compounds inhibited rape hypocotyl elongation, especially the indole-3-propionic acid derivatives, whose bioactivity was better than that of indole-3-acetic acid.

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