Two Distinct Epitopes on the Ovalbumin 323-339 Peptide Differentiating CD4⁺T Cells into the Th2 or Th1 Phenotype

DOI Web Site Web Site PubMed 被引用文献5件 参考文献35件
  • NAKAJIMA-ADACHI Haruyo
    Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The University of Tokyo Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Science, The University of Tokyo
  • KOIKE Emiko
    Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Science, The University of Tokyo
  • TOTSUKA Mamoru
    Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Science, The University of Tokyo
  • HIRAIDE Erika
    Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The University of Tokyo Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Science, The University of Tokyo
  • WAKATSUKI Yoshio
    Department of Clinical Bio-regulatory Science, Kyoto University Graduate School of Medicine Department of Clinical Bio-regulatory Science, Kyoto University Graduate School of Medicine
  • KIYONO Hiroshi
    Department of Mucosal Immunology, Institute of Medical Science, The University of Tokyo Department of Mucosal Immunology, Institute of Medical Science, The University of Tokyo
  • HACHIMURA Satoshi
    Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Science, The University of Tokyo Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Science, The University of Tokyo

書誌事項

タイトル別名
  • Two Distinct Epitopes on the Ovalbumin 323-339 Peptide Differentiating CD4<sup>+</sup>T Cells into the Th2 or Th1 Phenotype

この論文をさがす

抄録

The epitopes for OVA323-339-specific CD4+T cells from OVA23-3 food allergy model and DO11.10 tolerant induction model mice were analyzed. We found that OVA23-3 CD4+T cells recognized the N-terminal region, showing strong proliferation and the Th2-phenotype, and that DO11.10 CD4+T cells recognized the C-terminal region, showing milder proliferation and a Th1-skewed response. These differences may regulate the responses of those mice to OVA-feeding, inflammation and tolerance.

収録刊行物

被引用文献 (5)*注記

もっと見る

参考文献 (35)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ