Enzymatic Synthesis of Dehydroderivatives from Proline-Containing Cyclic Dipeptides and Their Effects toward Cell Division
-
- ARUNRATTIYAKORN Panarat
- Laboratory of Bioresources Chemistry, Graduate School of Natural Science and Technology, Okayama University
-
- IKEDA Banri
- Laboratory of Bioresources Chemistry, Graduate School of Natural Science and Technology, Okayama University
-
- NITODA Teruhiko
- Laboratory of Bioresources Chemistry, Graduate School of Natural Science and Technology, Okayama University
-
- KANZAKI Hiroshi
- Laboratory of Bioresources Chemistry, Graduate School of Natural Science and Technology, Okayama University
この論文をさがす
抄録
We have previously isolated cyclo(L-Pro-L-Tyr) and cyclo(L-Phe-L-Pro) from an actinomycete by a novel enzymatic conversion-guided method. Their tetradehydro derivatives, cyclo(ΔPro-ΔTyr) and cyclo(ΔPhe-ΔPro), were enzymatically prepared. Neither of them inhibited cell division, in contrast to other tetradehydro cyclic dipeptides prepared previously. This result suggests that an NH proton in a diketopiperazine ring and/or conformation of the compound are important for the activity.
収録刊行物
-
- Bioscience, Biotechnology, and Biochemistry
-
Bioscience, Biotechnology, and Biochemistry 71 (3), 830-833, 2007
公益社団法人 日本農芸化学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282681455110528
-
- NII論文ID
- 10027513130
-
- NII書誌ID
- AA10824164
-
- COI
- 1:STN:280:DC%2BD2s7otVKrsQ%3D%3D
-
- ISSN
- 13476947
- 09168451
-
- NDL書誌ID
- 8696522
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可