Impact of Spermine on Down-Regulation of Th2 Cytokines in Peripheral Blood Mononuclear Cells from Cedar Pollinosis Subjects<i>in Vitro</i>
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- MATSUMOTO Mitsuharu
- Dairy Science and Technology Institute, Kyodo Milk Industry Co., Ltd. Japan Collection of Microorganisms, RIKEN BioResourse Center
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- KIMATA Hiroichi
- Dairy Science and Technology Institute, Kyodo Milk Industry Co., Ltd.
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- BENNO Yoshimi
- Japan Collection of Microorganisms, RIKEN BioResourse Center
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- KAMIO Shigenori
- Ochiai Clinic
書誌事項
- タイトル別名
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- Impact of Spermine on Down-Regulation of Th2 Cytokines in Peripheral Blood Mononuclear Cells from Cedar Pollinosis Subjects in Vitro
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説明
The effects of spermine (SPM) on the production of Th1 and Th2 cytokines using peripheral blood mononuclear cells (PBMCs) derived from cedar pollinosis subjects were investigated. Th2 cytokines produced by PBMCs stimulated by 10 μM SPM was significantly lower than that in the controls. These findings indicate that blood SPM is an important factor in the Th1/Th2 balance.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 72 (6), 1604-1606, 2008
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681455414272
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- NII論文ID
- 10027529075
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- NII書誌ID
- AA10824164
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- COI
- 1:STN:280:DC%2BD1czpvFKntw%3D%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 9566839
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- PubMed
- 18540087
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可