The Inhibitory Effects of Catechins on Biofilm Formation by the Periodontopathogenic Bacterium, Eikenella corrodens
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- MATSUNAGA Tetsuro
- Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
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- NAKAHARA Aya
- Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
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- MINNATUL Karim M.
- Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University Department of Biothechnology and Genetic Engineering, Islamic University
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- NOIRI Yuichiro
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- EBISU Shigeyuki
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- KATO Akio
- Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
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- AZAKAMI Hiroyuki
- Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University
Bibliographic Information
- Other Title
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- The Inhibitory Effects of Catechins on Biofilm Formation by the Periodontopathogenic Bacterium,<i>Eikenella corrodens</i>
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Abstract
Eikenella corrodens is a periodontopathogenic bacterium that forms biofilm even by itself. In this study, we investigated the inhibitory effects of catechins on E. corrodens biofilm formation. Biofilm formation was inhibited by the addition of 1 mM of the catechins with the pyrogallol-type B-ring and/or the galloyl group. The catechins with the galloyl group were effective at smaller doses than those with only the pyrogallol-type B-ring. An inhibitory effect was observed even when these catechins and gallic acid were added at sub-minimal inhibitory concentration (MIC) or at concentrations that showed no bactericidal effect. These results suggest that some catechins at sub-MIC might inhibit biofilm formation. No inhibitory effect of catechins at sub-MIC on biofilm formation was observed in the luxS deletion mutant. Our studies suggest that some species of catechins with the galloyl group affect autoinducer 2-mediated quorum sensing and thereby inhibit biofilm formation by E. corrodens.
Journal
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 74 (12), 2445-2450, 2010
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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Keywords
Details 詳細情報について
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- CRID
- 1390282681455811840
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- NII Article ID
- 10027728071
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- NII Book ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL BIB ID
- 10928538
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed