Major water-soluble polyphenols, proanthocyanidins, in leaves of persimmon (Diospyros kaki) and their α-amylase inhibitory activity

  • KAWAKAMI Kayoko
    Department of Food Science, Niigata University of Pharmacy and Applied Life Sciences
  • AKETA Saiko
    Department of Food Science, Niigata University of Pharmacy and Applied Life Sciences
  • NAKANAMI Mitsuhiro
    Department of Food Science, Niigata University of Pharmacy and Applied Life Sciences
  • IIZUKA Shinzo
    Department of Food Science, Niigata University of Pharmacy and Applied Life Sciences
  • HIRAYAMA Masao
    Department of Food Science, Niigata University of Pharmacy and Applied Life Sciences

書誌事項

タイトル別名
  • Major Water-Soluble Polyphenols, Proanthocyanidins, in Leaves of Persimmon (Diospyros kaki) and Their .ALPHA.-Amylase Inhibitory Activity
  • Major water soluble polyphenols proanthocyanidins in leaves of persimmon Diospyros kaki and their a amylase inhibitory activity
  • Major Water-Soluble Polyphenols, Proanthocyanidins, in Leaves of Persimmon (<i>Diospyros kaki</i>) and Their α-Amylase Inhibitory Activity

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抄録

The amounts and compositions of polyphenol in persimmon leaves and persimmon leaf tea were investigated. The predominant polyphenols in fresh leaves were water-soluble, and the contents reached a maximum (2.40% w/w) in June, and then gradually decreased. Separation of them followed by thiolytic degradation revealed that the major components were unique proanthocyanidin oligomers consisting of four heterogeneous extension units, including epigallocatechin-3-O-gallate. Persimmon leaf tea also contained similar proanthocyanidins with similar compositional units. Oral administration of starch with polyphenol concentrate of persimmon leaf tea resulted in a significant and dose-dependent decrease in the blood glucose level in Wistar rats. This effect is considered to be due to inhibition of pancreas α-amylase. These results indicate that persimmon leaf tea containing peculiar proanthocyanidins has a significant role in suppressing blood glucose elevation after starch intake, and that the best harvest time is June.

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