Antioxidative Activity of Microbial Metabolites of (−)-Epigallocatechin Gallate Produced in Rat Intestines

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  • TAKAGAKI Akiko
    Laboratory of Tea Function R&D, Food Research Laboratories, Mitsui Norin Co., Ltd.
  • OTANI Shuichi
    Laboratory of Tea Function R&D, Food Research Laboratories, Mitsui Norin Co., Ltd.
  • NANJO Fumio
    Laboratory of Tea Function R&D, Food Research Laboratories, Mitsui Norin Co., Ltd.

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  • Antioxidative Activity of Microbial Metabolites of (-)-Epigallocatechin Gallate Produced in Rat Intestines

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The antioxidative activities of (−)-epigallocatechin gallate (EGCg) metabolites degraded by rat intestinal flora were investigated by a flow injection analysis coupled to an on-line antioxidant detection system with the 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation. All of the metabolites were found to have antioxidative activity, suggesting that the EGCg metabolites may show antioxidative activity in the body.

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