DPPH Radical Scavenging and Semicarbazide-Sensitive Amine Oxidase Inhibitory and Cytotoxic Activities of Taiwanofungus camphoratus (Chang-Chih)

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  • WANG Guei-Jane
    National Research Institute of Chinese Medicine
  • LIN Shyr-Yi
    Department of Internal Medicine, School of Medicine, Taipei Medical University Department of Internal Medicine, Taipei Medical University Hospital Traditional Herbal Medicine Research Center, Taipei Medical University Hospital
  • WU Wen-Chun
    Graduate Institute of Pharmacognosy, Taipei Medical University
  • HOU Wen-Chi
    Graduate Institute of Pharmacognosy, Taipei Medical University Traditional Herbal Medicine Research Center, Taipei Medical University Hospital

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  • DPPH Radical Scavenging and Semicarbazide-Sensitive Amine Oxidase Inhibitory and Cytotoxic Activities of<i>Taiwanofungus camphoratus</i>(Chang-Chih)

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Abstract

Wild, liquid state culture and solid state culture of Taiwanofungus camphoratus (Chang-chih) were sequentially extracted with cold water, methanol, and hot water to get cold water soluble, methanol soluble, and hot water soluble extracts respectively. The extracts from three Chang-chih were used to determine 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, semicarbazide sensitive amine oxidase inhibitory, and cytotoxic activities against B16-F10 and HT-1080 cell lines. It was found that extracted fractions from three Chang-chih exhibited the different levels of biological activities.

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