Cellular Responses to Electrochemical Killing Process by Applying a Constant Potential in Synchronously Cultured Saccharomyces Cerevisiae

DOI Web Site 参考文献8件 オープンアクセス
  • TAKEYAMA Haruko
    Department of Biotechnology, Tokyo University of Agriculture and Technology
  • SUZUKI Takeyuki
    Department of Biotechnology, Tokyo University of Agriculture and Technology
  • OKAMURA Yoshiko
    Department of Biotechnology, Tokyo University of Agriculture and Technology
  • MORI Tetsushi
    Department of Biotechnology, Tokyo University of Agriculture and Technology
  • MATSUNAGA Tadashi
    Department of Biotechnology, Tokyo University of Agriculture and Technology

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タイトル別名
  • Cellular Responses to Electrochemical Killing Process by Applying a Constant Potential in Synchronously Cultured <i>Saccharomyces Cerevisiae</i>

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説明

To elucidate the mechanism of the electrochemical killing, the global gene expression of synchronously cultured Saccharomyces cerevisiae exposed to electrochemical stimulus was analyzed using DNA microarray. By applying a potential of 1.0 V vs. saturated calomel electrode (SCE), oxidative stress related genes were expressed after only 5 minutes. The gene for cta1 exhibited the highest expression level, while ROS gradually accumulated inside the cells. Genes for signal transduction which may be related to cellular apoptosis were also seen expressed.

収録刊行物

  • Electrochemistry

    Electrochemistry 76 (8), 603-605, 2008

    公益社団法人　電気化学会

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