Hydrogel of High Water Content as a Material for the Soft Contact Lens
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- HOSAKA Shuntaro
- Basic Research Laboratory, Toray Industries, Inc.
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- MORI Yuichi
- Basic Research Laboratory, Toray Industries, Inc.
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- KENJO Hideki
- Basic Research Laboratory, Toray Industries, Inc.
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- TANZAWA Hiroshi
- Basic Research Laboratory, Toray Industries, Inc.
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- MOMOSE Takayuki
- Department of Ophthalmology, School of Medicine, Juntendo University
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- MAGATANI Hisao
- Department of Ophthalmology, School of Medicine, Juntendo University
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- NAKAJIMA Akira
- Department of Ophthalmology, School of Medicine, Juntendo University
Bibliographic Information
- Other Title
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- ソフトコンタクトレンズ材料としての高含水率ハイドロゲル
- ソフト コンタクト レンズ ザイリョウ トシテノ コウ ガンスイリツ ハイドロ
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Abstract
A hydrogel of high water content was applied for the soft contact lens capable of being worn continuously. The hydrogels prepared in this study contain methyl methacrylate units as hydrophobic component and N-viny1-2-pyrrolidone units as hydrophilic component. Oxygen permeability and tensile strength of the hydrogels were measured at 52% 90% water content. From the both properties mentioned above and the reported values of oxygen uptake by front surface of human cornea, it is anticipated that the contact lens of about 70% water content and 0.15 mm thickness can be worn continuously in sleep. In clinical tests, 69 myopic patients wore continuously the contact lenses of 70% water content and 0.15-0.20mm thickness at the center, without any symptom of hypoxia at the cornea for 1-25 months. On the other hand, several cases among the 78 aphakic patients were suspected of hypoxia at the corneas. They wore the contact lenses of the same material but of 0.50-0.60 mm center thickness continuously for the same period as the above.
Journal
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- KOBUNSHI RONBUNSHU
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KOBUNSHI RONBUNSHU 36 (4), 265-271, 1979
The Society of Polymer Science, Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390282681500396160
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- NII Article ID
- 130004033827
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- NII Book ID
- AN00085011
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- ISSN
- 18815685
- 03862186
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- NDL BIB ID
- 2050675
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed