顎下腺に発生した上皮筋上皮癌の１例

DOI 被引用文献1件 参考文献10件

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  • Epithelial-myoepithelial carcinoma of the submandibular gland: A case report.

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Epithelial-myoepithelial carcinoma (EMC) comprises less than 1% of all salivary gland neoplasms and is essentially a tumor confined to the major glands, particularly the parotid (80%). A case of epithelial-myoepithelial carcinoma of the submandibular gland is reported. An 85-year-old man had a painless mass in the left submandibular region for 4 years. The mass was removed with the left submandibular gland. Histologically, the tumor consisted of a proliferation of double-layered duct-like structures with two distinctive cell types. On immunohistochemical analysis, reaction products for keratin and EMA were predominantly found in the inner epithelial cells, while those for smooth muscle actin and S-100 protein were observed in the outer epithelial cells. The patient showed no recurrence or metastasis for 2 years 2 months after surgical resection of the tumor tissue.

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