A case of double cancer involving mucoepidermoid carcinoma and thymoma

KON Hideki, HAMADA Tomohiro, KASAI Keiko, SONODA Masahito, OHNO Takashi

doi:10.5794/jjoms.56.213

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下顎臼後部に発生した粘表皮癌と胸腺腫の重複腫瘍の1例
カガクキュウコウブニハッセイシタネンヒョウヒガントキョウセンシュノチョウフクシュヨウノ 1レイ

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Abstract

Mucoepidermoid carcinoma, a type of malignant tumor of the salivary glands, is characterized by mucous, squamous, and intermediate cells and mainly arises in the major salivary glands, especially the parotid and palatine glands. We report a rare case of double cancer involving a mucoepidermoid carcinoma and a thymoma, with a review of the literature. A 45-year-old man was referred to our hospital bacause of a feeling of incongruity in the left retromolar region of the mandible. Histologic examination of a biopsy specimen revealed well-differentiated (low-grade malignancy) mucoepidermoid carcinoma. After marginal resection of the mandible, fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography clearly demonstrated strong FDG uptake in the anterior mediastinum (SUV max: 5.8), which suggested a tumor. The thymus was surgically excised, and the definitive diagnosis was thymoma. These results suggested a rare case of double cancer involving mucoepidermoid carcinoma in the retromolar region and thymoma (WHO Type B2). There was no evidence of local recurrence or distant metastasis 2 years 1 month after the operation.

Journal

Japanese Journal of Oral and Maxillofacial Surgery

Japanese Journal of Oral and Maxillofacial Surgery 56 (3), 213-217, 2010

Japanese Society of Oral and Maxillofacial Surgeons

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