Analysis of platelet aggregation and TGF-.BETA. content in platelet-rich plasma

DOI Web Site 1 Citations 19 References
  • WATATANI Sanae
    Department of Oral and Maxillofacial Surgery, Kobe University, Graduate School of Medicine
  • YANAGIDA Megumi
    Department of Oral and Maxillofacial Surgery, Kobe University, Graduate School of Medicine
  • SUZUKI Hiroaki
    Department of Oral and Maxillofacial Surgery, Kobe University, Graduate School of Medicine
  • YOKOO Satoshi
    Department of Oral and Maxillofacial Surgery, Kobe University, Graduate School of Medicine
  • KOMORI Takahide
    Department of Oral and Maxillofacial Surgery, Kobe University, Graduate School of Medicine

Bibliographic Information

Other Title
  • 多血小板血漿の血小板凝集能とＴＧＦ‐β含有量に関する解析
  • タケッショウバン ケッショウ ノ ケッショウバン ギョウシュウノウ ト TGF ベータ ガンユウリョウ ニ カンスル カイセキ

Search this article

Abstract

Recently, platelet-rich plasma (PRP) has been used clinically to promote bone regeneration and wound healing. However, no study has clearly reported on the activity of PRP after preparation. We established a protocol for the safe production of PRP from small quantities of blood.<BR>Various conditions were used for anticoagulants and centrifugal separation speed for blood samples obtained from 23 healthy subjects to investigate optimal concentration conditions. Our results showed that when 20% ACD-A liquid was used as the anticoagulant, PRP was most efficiently obtained by double centrifugation at 800 r. p. m. and 1300 r.p.m. The effectiveness of PRP was confirmed by platelet aggregation reaction and the TGF-β content of PRP after double centrifugation.

Journal

Citations (1)*help

See more

References(19)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top