Molecular Motor, Dynein is an Oscillating Force Generator.

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  • SHINGYOJI Chikako
    Department of Biological Science, Graduate School of Science, University of Tokyo

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  • 振動する生物分子モーター「ダイニン」
  • シンドウ スル セイブツ ブンシ モーター ダイニン

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Abstract

One of the prominent features of flagellar movement is oscillation (or cyclical beating). The motive force for the bending is the sliding induced by dynein arms between adjacent doublet microtubules in the flagellar axonemes. To generate oscillatory bending, the activity of dynein should be regulated. The central pair apparatus, which locates at the center of the axoneme, seems to be involved in this regulation. Our recent finding of the oscillation of force in dynein revealed that the dynein molecule itself may be related to the oscillation of the flagellar movement.

Journal

  • Seibutsu Butsuri

    Seibutsu Butsuri 40 (2), 111-116, 2000

    The Biophysical Society of Japan General Incorporated Association

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