下顎骨に転移が認められた網膜芽細胞腫の1例

  • 大場 誠悟
    福井大学医学部感覚運動医学講座歯科口腔外科学領域
  • 谷澤 昭彦
    福井大学医学部病態制御医学講座小児科学領域
  • 吉村 仁志
    福井大学医学部感覚運動医学講座歯科口腔外科学領域
  • 松田 慎平
    福井大学医学部感覚運動医学講座歯科口腔外科学領域
  • 今村 好章
    福井大学医学部附属病院病理部
  • 佐野 和生
    福井大学医学部感覚運動医学講座歯科口腔外科学領域

書誌事項

タイトル別名
  • A case of retinoblastoma metastasizing to the mandible
  • カガクコツ ニ テンイ ガ ミトメラレタ モウマクガ サイボウ シュ ノ 1レイ

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抄録

Retinoblastoma is a malignant tumor originally derived from the immature retina in infancy and childhood. It usually occurs in patients younger than 2 years. Although the prognosis after treatment is relatively good, the prognosis becomes poor if extraocular extension, distant metastases, or both occur. A 1 and a half-year-old male had been given a diagnosis of a retinoblastoma of the left eye and received conservative treatment. A recurrent tumor was later found, and metastatic tumors were detected in the bone marrow, femur, and mandible 6 months later. Chemotherapy was performed at that time. Thereafter, enucleation of the left eye and peripheral blood stem-cell transplantation with ultra-high-dose chemotherapy were performed. Consequently, cerebrospinal irradiation was also performed. The patient has been in remission for 6 years. The mandible has no findings of recurrence and no dysgenesis. The permanent teeth have nearly all erupted with short roots and provide good occlusion.

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