A case of carcinoma ex pleomorphic adenoma in the submandibular region

  • KINOSHITA Koji
    Department of Dentistry, Maxillofacial Surgery, Toyooka Hospital
  • YASUDA Shinya
    Department of Dentistry, Maxillofacial Surgery, Toyooka Hospital
  • NISHIDA Mitsuo
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University
  • HORI Shinsuke
    Department of Oral and Maxillofacial Surgery, Kumihama Hospital
  • YAMADA Michihiro
    Department of Dentistry, Maxillofacial Surgery, Toyooka Hospital
  • TOGO Yumiko
    Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University

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Other Title
  • 顎下部に発生した多形腺腫由来癌の1例
  • ガクカブ ニ ハッセイ シタ タケイ センシュ ユライガン ノ 1レイ

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Abstract

This report describes a case of carcinoma ex pleomorphic adenoma originating from a recurrent pleomorphicadenoma in a 67-year-old woman. She was referred to our department because of a swelling in the rightcervical region. At presentation, a painless elastic hard tumor measuring 40 X 30mm was located in the right sideof the upper neck.<br>Computed tomography and magnetic resonance imaging showed enhancement of a nodule and a segmentedmass. The biopsy diagnosis was a carcinoma ex pleomorphic adenoma.<br>A radical neck dissection, including the tumor, was performed. Histological examination revealed a rare undifferentiatedcarcinoma. The final diagnosis was a carcinoma ex pleomorphic adenoma because the patient had previouslyundergone a resection of a ipsilateral submandibular pleomorphic adenoma showing atypia and intracapsularinvasion.<br>There has been no sign of recurrence or metastasis for 4 years 8 months postoperatively.

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