A patient with hereditary hemorrhagic telangiectasia who underwent resection of an upper gingival carcinoma
-
- YOSHIMURA Hitoshi
- Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui
-
- AIDA Yusuke
- Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui
-
- KONDO Hiroko
- Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui
-
- TOBITA Takayoshi
- Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui
-
- UENO Takaaki
- Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui Department of Dentistry and Oral Surgery, Division of Medicine for Function and Morphology of Sensory Organs, Osaka Medical College
-
- SANO Kazuo
- Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui
Bibliographic Information
- Other Title
-
- 上顎歯肉癌に対し腫瘍切除を施行した遺伝性出血性毛細血管拡張症の1例
- ウワアゴ シニクガン ニ タイシ シュヨウ セツジョ オ シコウ シタ イデンセイ シュッケツセイ モウサイケッカン カクチョウショウ ノ 1レイ
Search this article
Abstract
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant inherited disorder affecting blood vessels of the skin, mucous membranes and viscera. A definite diagnosis of HHT is made in the presence of at least three of the Curaçao criteria: (1) epistaxis, (2) telangiectasias, (3) visceral lesions, and (4) a family history. We describe a case of upper gingival carcinoma in a patient with HHT. A 79-year-old woman visited our department because of an upper gingival mass. A biopsy specimen revealed squamous cell carcinoma. Preoperative examination revealed consistency with three of the above criteria: (2) skin and mucosal telangiectasias, (3) gastrointestinal telangiectasia and pulmonary and hepatic arteriovenous malformations (AVMs), and (4) mucosal telangiectasia and pulmonary AVM in her daughter. HHT was definitely diagnosed. Tumorectomy was scheduled; however, HHT-associated complications such as bleeding, hypoxemia, cerebral thromboembolism, and AVM rupture were expected. Tumor resection by partial maxillectomy and reconstruction with a buccal fat pad were performed under general anesthesia. The postoperative course was uneventful, and follow-up at 1.5 years showed no evidence of tumor recurrence or metastasis. We conclude that recognition of hemorrhagic tendencies and evaluation of systemic AVMs are critical before surgical treatment in patients with HHT.
Journal
-
- Japanese Journal of Oral and Maxillofacial Surgery
-
Japanese Journal of Oral and Maxillofacial Surgery 58 (4), 257-261, 2012
Japanese Society of Oral and Maxillofacial Surgeons
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282681508537984
-
- NII Article ID
- 130004707899
- 10031144887
-
- NII Book ID
- AN00189163
-
- ISSN
- 21861579
- 00215163
-
- NDL BIB ID
- 023749906
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
-
- Abstract License Flag
- Disallowed