書誌事項
- タイトル別名
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- 5-Fluorouracil leukoencephalopathy occuring during postoperative chemotherapy in a patient with tongue cancer: a case report
- ゼツガン カンジャ ノ ジュツゴ カガク リョウホウ チュウ ニ ショウジタ 5FU ハクシツ ノウショウ ノ 1レイ
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5-Fluorouracil leukoencephalopathy presents with various types of neuropathy, including disturbed consciousness, psychological symptoms, and motor symptoms. This report presents a case of 5-fluorouracil leukoencephalopathy that occurred during postoperative chemotherapy in a patient with tongue cancer.<br>A 21-year-old postoperative patient with tongue cancer received chemotherapy （with 80mg / m2 cisplatin on day 1 and 1000 mg / 5-Fluorouracil on days 1-5）.<br>5-Fluorouracil was discontinued because psychological symptoms and tonic convulsion began on day 5 of chemotherapy. The patient was given a diagnosis of leukoencephalopathy because brain MRI showed a bilateral, symmetric high-signal-intensity lesion involving the white matter. The patient was observed closely without any therapy and recovered 6 days after the onset of leukoencephalopathy. Leukoencephalopathy can occur during chemotherapy with 5-fluorouracil, and it is important to diagnose this condition at an early stage and immediately discontinue treatment with 5-fluorouracil.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 58 (8), 494-498, 2012
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681508692736
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- NII論文ID
- 130004714370
- 10031144929
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 023959319
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
