A case of thyroid carcinoma diagnosed by metastasis to the mandible
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- HYODO Tomoko
- Department of Dentistry and Oral Surgery, Tokyo Metropolitan Tama Medical Center
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- MIGITA Masashi
- Department of Dentistry and Oral Surgery, Tokyo Metropolitan Tama Medical Center
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- KAMIYAMA Isao
- Department of Dentistry and Oral Surgery, Tokyo Metropolitan Tama Medical Center
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- NISHIHORI Youhei
- Department of Dentistry and Oral Surgery, Tokyo Metropolitan Tama Medical Center
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- SHIGEMATSU Shirou
- Department of Dentistry and Oral Surgery, Tokyo Metropolitan Tama Medical Center
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- OHATA Hitoshi
- Department of Oral and Maxillofacial Surgery, Tokyo Dental College
Bibliographic Information
- Other Title
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- 下顎骨転移病変より確定診断が得られた甲状腺癌の1例
- カガクコツ テンイ ビョウヘン ヨリ カクテイ シンダン ガ エラレタ コウジョウセンガン ノ 1レイ
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Abstract
A follicular carcinoma of the thyroid can be difficult to differentiate from a follicular adenoma, a benign tumor of the thyroid, on the basis of histopathological findings. In such cases, the tumor is not diagnosed as malignant until distant metastasis develops. We report a case of follicular carcinoma of the thyroid that was definitively diagnosed when an osteolytic lesion developed in the right mandibular ramus. A 66-year-old woman visited our department because of gingival swelling at the posterior part of the right mandibular molar region. Diagnostic imaging revealed a mandibular lesion that had destroyed the inside of the bone and then progressed outward. In addition, a calcified lesion was found in the left lobe of the thyroid gland, and evidence suggesting multiple bone and lung metastases was also found. A biopsy of the mandibular lesion indicated that bone metastasis from a thyroid carcinoma was most likely. However, the histopathological diagnosis of the excised thyroid specimen was follicular adenoma, thus casting doubt on the possibility of metastasis from the mandibular lesion.<br>A segmental resection of the mandible was performed as radical treatment for the mandibular lesion because it showed a trend toward enlargement. Histopathological examination of the resected lesion showed scant cellular atypia; however, it was definitively diagnosed as a follicular carcinoma of the thyroid on the basis of osteolytic findings in the specimen and distal metastasis to the mandible.
Journal
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- Japanese Journal of Oral and Maxillofacial Surgery
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Japanese Journal of Oral and Maxillofacial Surgery 59 (10), 637-642, 2013
Japanese Society of Oral and Maxillofacial Surgeons
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Details 詳細情報について
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- CRID
- 1390282681509626752
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- NII Article ID
- 40019842114
- 130004793854
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- NII Book ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL BIB ID
- 024956124
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed